1. Graduate School of Pharmaceutical Sciences, Kyoto University, Sakyo-ku, Kyoto 606-8501, Japan, Kharkov National University, 4 Svoboda Square, Kharkov, 61077, Ukraine, Osaka Branch, National Institute of Health Sciences, Osaka 540-0006, Japan, and Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 16/10 Miklukho-Maklaya, Moscow, 117871, Russia