A General Method for Making Peptide Therapeutics Resistant to Serine Protease Degradation: Application to Dipeptidyl Peptidase IV Substrates-Reference-Cited by-同舟云学术

A General Method for Making Peptide Therapeutics Resistant to Serine Protease Degradation: Application to Dipeptidyl Peptidase IV Substrates

Published:2013-10-16 Issue:21 Volume:56 Page:8339-8351
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Heard Kathryn R.¹,Wu Wengen¹,Li Youhua¹,Zhao Peng¹,Woznica Iwona¹,Lai Jack H.¹,Beinborn Martin²,Sanford David G.¹,Dimare Matthew T.¹,Chiluwal Amrita K.¹,Peters Diane E.¹,Whicher Danielle¹,Sudmeier James L.¹,Bachovchin William W.¹

Affiliation:

1. Department of Biochemistry, Tufts University Sackler School of Graduate Biomedical Sciences, 136 Harrison Avenue, Boston, Massachusetts 02111, United States

2. Molecular Pharmacology Research Center, Molecular Cardiology Research Institute, Tufts Medical Center, 800 Washington Street, Boston, Massachusetts 02111, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm400423p

Reference58 articles.

1. Discovering and improving novel peptide therapeutics

2. Dipeptidyl-peptidase IV (CD26)-role in the inactivation of regulatory peptides

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