A Remote Arene-Binding Site on Prostate Specific Membrane Antigen Revealed by Antibody-Recruiting Small Molecules-Reference-Cited by-同舟云学术

A Remote Arene-Binding Site on Prostate Specific Membrane Antigen Revealed by Antibody-Recruiting Small Molecules

Published:2010-08-20 Issue:36 Volume:132 Page:12711-12716
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

Zhang Andrew X.¹,Murelli Ryan P.¹,Barinka Cyril¹,Michel Julien¹,Cocleaza Alexandra¹,Jorgensen William L.¹,Lubkowski Jacek¹,Spiegel David A.¹

Affiliation:

1. Department of Chemistry, Yale University, 225 Prospect Street, P.O. Box 208107, New Haven, Connecticut 06510-8107, Laboratory of Structural Biology, Institute of Biotechnology AS CR, v.v.i., 14200 Prague 4, Czech Republic, Macromolecular Crystallography Laboratory, 539 Boyles Street, National Cancer Institute at Frederick, Frederick, Maryland 21702, and Department of Pharmacology, Yale University School of Medicine, 333 Cedar Street, New Haven, Connecticut 06520

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Link

https://pubs.acs.org/doi/pdf/10.1021/ja104591m

Reference72 articles.

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2. Clinical Trials of Cancer Therapies Targeting Prostate-Specific Membrane Antigen

3. Chemical Control over Immune Recognition: A Class of Antibody-Recruiting Small Molecules That Target Prostate Cancer

4. For lead examples of other bifunctional materials that redirect antibodies to target cells, see:

5. An Antibody-Recruiting Small Molecule That Targets HIV gp120

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