Synthesis and Evaluation of 5-Substituted 2′-deoxyuridine Monophosphate Analogues As Inhibitors of Flavin-Dependent Thymidylate Synthase in Mycobacterium tuberculosis-Reference-Cited by-同舟云学术

Synthesis and Evaluation of 5-Substituted 2′-deoxyuridine Monophosphate Analogues As Inhibitors of Flavin-Dependent Thymidylate Synthase in Mycobacterium tuberculosis

Published:2011-06-09 Issue:13 Volume:54 Page:4847-4862
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Kögler Martin¹,Vanderhoydonck Bart²,De Jonghe Steven²,Rozenski Jef¹,Van Belle Kristien²,Herman Jean²,Louat Thierry²,Parchina Anastasia¹,Sibley Carol³,Lescrinier Eveline¹,Herdewijn Piet¹

Affiliation:

1. Katholieke Universiteit Leuven, Rega Institute for Medical Research, Laboratory of Medicinal Chemistry, Minderbroedersstraat 10, 3000 Leuven, Belgium

2. Katholieke Universiteit Leuven, Interface Valorisation Platform (IVAP), Kapucijnenvoer 33, 3000 Leuven, Belgium

3. Department of Genome Sciences, University of Washington, Seattle, Washington, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm2004688

Reference59 articles.

1. World Health Organization Global TB Control Report, 2010.

2. The resumption of consumption: a review on tuberculosis

3. Microbial Pathogenesis of Mycobacterium tuberculosis: Dawn of a Discipline

4. Antituberculosis drugs: Ten years of research

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