Flexibility of Human Cytochromes P450: Molecular Dynamics Reveals Differences between CYPs 3A4, 2C9, and 2A6, which Correlate with Their Substrate Preferences-Reference-Cited by-同舟云学术

Flexibility of Human Cytochromes P450: Molecular Dynamics Reveals Differences between CYPs 3A4, 2C9, and 2A6, which Correlate with Their Substrate Preferences

Published:2008-06-17 Issue:27 Volume:112 Page:8165-8173
ISSN:1520-6106
Container-title:The Journal of Physical Chemistry B
language:en
Short-container-title:J. Phys. Chem. B

Author:

Skopalík Josef¹,Anzenbacher Pavel¹,Otyepka Michal¹

Affiliation:

1. Department of Physical Chemistry and Center for Biomolecules and Complex Molecular Systems, Palacky University, Trida Svobody 26, 771 46, Olomouc, Czech Republic, and Department of Pharmacology, Faculty of Medicine and Dentistry, Palacky University, Hnevotinska 3, 775 15 Olomouc, Czech Republic

Publisher

American Chemical Society (ACS)

Subject

Materials Chemistry,Surfaces, Coatings and Films,Physical and Theoretical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/jp800311c

Reference44 articles.

1. Cytochrome P450

2. Pharmacogenomics: Translating Functional Genomics into Rational Therapeutics

3. Cytochromes P450 and metabolism of xenobiotics

4. Common and Uncommon Cytochrome P450 Reactions Related to Metabolism and Chemical Toxicity

5. Summary of information on human CYP enzymes: human P450 metabolism data

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