Discovery of a Potent and Selective α3β4 Nicotinic Acetylcholine Receptor Antagonist from an α-Conotoxin Synthetic Combinatorial Library-Reference-Cited by-同舟云学术

Discovery of a Potent and Selective α3β4 Nicotinic Acetylcholine Receptor Antagonist from an α-Conotoxin Synthetic Combinatorial Library

Published:2014-04-03 Issue:8 Volume:57 Page:3511-3521
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Chang Yi-Pin¹,Banerjee Jayati¹,Dowell Cheryl²³,Wu Jinhua¹,Gyanda Reena¹,Houghten Richard A.¹,Toll Lawrence¹,McIntosh J. Michael²³,Armishaw Christopher J.¹

Affiliation:

1. Torrey Pines Institute for Molecular Studies, 11350 SW Village Parkway, Port St. Lucie, Florida 34987, United States

2. George E. Wahlen Veterans Affairs Medical Center, Salt Lake City, Utah 84108, United States

3. Departments of Psychiatry and Biology, University of Utah, Salt Lake City, Utah 84112, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm500183r

Reference50 articles.

1. Nicotinic receptors: allosteric transitions and therapeutic targets in the nervous system

2. Nicotinic Acetylcholine Receptors and Nicotinic Cholinergic Mechanisms of the Central Nervous System

3. Neuronal Nicotinic Acetylcholine Receptors: Structural Revelations, Target Identifications, and Therapeutic Inspirations

4. Nicotine aversion: Neurobiological mechanisms and relevance to tobacco dependence vulnerability

5. Varenicline

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