Generation of New Cytotoxic Human Ribonuclease Variants Directed to the Nucleus-Reference-Cited by-同舟云学术

Generation of New Cytotoxic Human Ribonuclease Variants Directed to the Nucleus

Published:2012-09-20 Issue:10 Volume:9 Page:2894-2902
ISSN:1543-8384
Container-title:Molecular Pharmaceutics
language:en
Short-container-title:Mol. Pharmaceutics

Author:

Vert Anna¹,Castro Jessica¹,Ruiz-Martínez Santiago¹,Tubert Pere¹,Escribano Diego¹,Ribó Marc¹,Vilanova Maria¹,Benito Antoni¹

Affiliation:

1. Laboratori d’Enginyeria de Proteïnes, Departament de Biologia, Facultat de Ciències, Universitat de Girona, Campus de Montilivi, M. Aurélia Campmany, 69 17071 Girona, Spain, and Institut d’Investigació Biomèdica de Girona Dr. Josep Trueta (IdIBGi), Girona, Spain

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/mp300217b

Reference41 articles.

1. Antitumor Ribonucleases

2. Induction of differentiation of leukaemic (HL-60) or prostate cancer (LNCaP, JCA-1) cells potentiates apoptosis triggered by onconase

3. Remarkable enhancement of cytotoxicity of onconase and cepharanthine when used in combination on various tumor cell lines

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