Diamine-Free Lithiation−Trapping of N-Boc Heterocycles using s-BuLi in THF
Author:
Affiliation:
1. Department of Chemistry, University of York, Heslington, York YO10 5DD, U.K., and Department of Process Research, Merck Research Laboratories, Rahway, New Jersey 07065
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/ol1017799
Reference34 articles.
1. α-Lithioamine synthetic equivalents from dipole-stabilized carbanions: The t-Boc group as an activator for α′-lithiation of carbamates
2. .alpha.-Lithioamine synthetic equivalents: syntheses of diastereoisomers from Boc derivatives of cyclic amines
3. Catalytic asymmetric synthesis of the alkaloid (+)-myrtine
4. Pd-Catalyzed Enantioselective Aerobic Oxidation of Secondary Alcohols: Applications to the Total Synthesis of Alkaloids
5. Synthesis of 2-substituted piperazines via direct α-lithiation
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