Detection of Glial Fibrillary Acidic Protein in Patient Plasma Using On-Chip Graphene Field-Effect Biosensors, in Comparison with ELISA and Single-Molecule Array

Author:

Xu Lizhou1,Ramadan Sami1ORCID,Akingbade Oluwatomi E.23,Zhang Yuanzhou1,Alodan Sarah1,Graham Neil23,Zimmerman Karl A.23,Torres Elias4,Heslegrave Amanda56,Petrov Peter K.1ORCID,Zetterberg Henrik56789,Sharp David J.23,Klein Norbert1,Li Bing23ORCID

Affiliation:

1. Department of Materials, Imperial College London, London SW7 2AZ, U.K.

2. Department of Brain Sciences, Imperial College London, London W12 0BZ, U.K.

3. Care Research & Technology Centre, UK Dementia Research Institute, London W12 0BZ, U.K.

4. Graphenea Semiconductor, Paseo Mikeletegi 83, San Sebastián 20009, Spain

5. UK Dementia Research Institute at UCL, University College London, London WC1E 6BT, U.K.

6. Department of Neurodegenerative Disease, UCL Institute of Neurology, London WC1E 6BT, U.K.

7. Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, the Sahlgrenska Academy at the University of Gothenburg, Mölndal 43141, Sweden

8. Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal 43141, Sweden

9. Hong Kong Centre for Neurodegenerative Diseases, Hong Kong 999077, China

Funder

Engineering and Physical Sciences Research Council

Alzheimer's Drug Discovery Foundation

Stiftelsen f??r Gamla Tj??narinnor

Medical Research Council

Vetenskapsr??det

Alzheimer's Association

National Institute for Health Research

H2020 Marie Sk??odowska-Curie Actions

UK Dementia Research Institute

Familjen Erling-Perssons Stiftelse

H2020 European Research Council

Imperial College Healthcare NHS Trust

Olav Thon Foundation

Swedish State Support for Clinical Research

Publisher

American Chemical Society (ACS)

Subject

Fluid Flow and Transfer Processes,Process Chemistry and Technology,Instrumentation,Bioengineering

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