Engineering a Point-of-Care Paper-Microfluidic Electrochemical Device Applied to the Multiplexed Quantitative Detection of Biomarkers in Sputum

Author:

Gutiérrez-Capitán Manuel1ORCID,Sanchís Ana23,Carvalho Estela O.4,Baldi Antonio1,Vilaplana Lluïsa23,Cardoso Vanessa F.45ORCID,Calleja Álvaro1,Wei Mingxing6,de la Rica Roberto78ORCID,Hoyo Javier9ORCID,Bassegoda Arnau9,Tzanov Tzanko9ORCID,Marco María-Pilar23ORCID,Lanceros-Méndez Senentxu41011,Fernández-Sánchez César13ORCID

Affiliation:

1. Instituto de Microelectrónica de Barcelona, IMB-CNM (CSIC), Campus UAB, 08193 Bellaterra, Spain

2. Nanobiotechnology for Diagnostics (Nb4D), Institute for Advanced Chemistry of Catalonia (IQAC), CSIC, 08034 Barcelona, Spain

3. Centro de Investigación Biomédica en Red de Bioingeniería, Biomateriales y Nanomedicina (CIBER-BBN), 28029 Madrid, Spain

4. Centre of Physics of the Universities of Minho and Porto (CF-UM-UP) and LaPMET, 4710-057 Braga, Portugal

5. CMEMS-UMinho, 4800-058 Guimarães, Portugal

6. Cellvax, SAS, 94800 Villejuif, France

7. Multidisciplinary Sepsis Group, Health Research Institute of the Balearic Islands (IdISBa), 07120 Palma de Mallorca, Spain

8. Centro de Investigación Biomédica en Red de Enfermedades Infecciosas (CIBER-INFEC), 28029 Madrid, Spain

9. Grup de Biotecnologia Molecular i Industrial, Departament d’Enginyeria Química, Universitat Politècnica de Catalunya, 08222 Terrassa, Spain

10. Basque Centre for Materials and Applications (BCMaterials), UPV/EHU, 48940 Leioa, Spain

11. IKERBASQUE, 48009 Bilbao, Spain

Funder

Consejo Superior de Investigaciones Científicas

European Commission

Ministerio de Ciencia e Innovación

Secretaría de Estado de Investigación, Desarrollo e Innovación

Fundação para a Ciência e a Tecnologia

Publisher

American Chemical Society (ACS)

Subject

Fluid Flow and Transfer Processes,Process Chemistry and Technology,Instrumentation,Bioengineering

Reference54 articles.

1. World Health Organization (WHO) Global Health Estimates: Key Figures and Tables. https://www.who.int/news-room/fact-sheets/detail/the-top-10-causes-of-death (accessed Feb 01, 2023).

2. NonCommunicable Diseases Team. Global action plan for the prevention and control of NCDs 2013-2020. https://apps.who.int/gb/ebwha/pdf_files/WHA66/A66_R10-en.pdf?ua=1 (accessed Feb 01, 2023).

3. Biomarkers in chronic obstructive pulmonary disease: confusing or useful?

4. TNF-α-, TNF-β-, IL-6-, and IL-10-promoter polymorphisms in patients with chronic obstructive pulmonary disease

5. Sputum myeloperoxidase in chronic obstructive pulmonary disease

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