Phenylpyrazolo[1,5-a]quinazolin-5(4H)-one: A Suitable Scaffold for the Development of Noncamptothecin Topoisomerase I (Top1) Inhibitors-Reference-Cited by-同舟云学术

Phenylpyrazolo[1,5-a]quinazolin-5(4H)-one: A Suitable Scaffold for the Development of Noncamptothecin Topoisomerase I (Top1) Inhibitors

Published:2013-09-16 Issue:18 Volume:56 Page:7458-7462
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Taliani Sabrina¹,Pugliesi Isabella¹,Barresi Elisabetta¹,Salerno Silvia¹,Marchand Christophe²,Agama Keli²,Simorini Francesca¹,La Motta Concettina¹,Marini Anna Maria¹,Di Leva Francesco Saverio³,Marinelli Luciana⁴,Cosconati Sandro⁵,Novellino Ettore⁴,Pommier Yves²,Di Santo Roberto⁶,Da Settimo Federico¹

Affiliation:

1. Department of Pharmacy, University of Pisa, via Bonanno 6, 56126 Pisa, Italy

2. Laboratory of Molecular Pharmacology, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland 20892-4255, United States

3. Department of Drug Discovery and Development, Istituto Italiano di Tecnologia (IIT), Via Morego 30, 16163 Genova, Italy

4. Department of Pharmacy, University of Naples “Federico II”, Via D. Montesano 49, 80131 Napoli, Italy

5. DiSTABiF, Seconda Università di Napoli, Via G. Vivaldi 43, 81100 Caserta, Italy

6. Istituto Pasteur—Fondazione Cenci Bolognetti, Dipartimento di Chimica e Tecnologie del Farmaco, “Sapienza” Università di Roma, P.le Aldo Moro 5, I-00185, Rome, Italy

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm400932c

Reference21 articles.

1. Cellular roles of DNA topoisomerases: a molecular perspective

2. Drugging Topoisomerases: Lessons and Challenges

3. Plant Antitumor Agents. I. The Isolation and Structure of Camptothecin, a Novel Alkaloidal Leukemia and Tumor Inhibitor from Camptotheca acuminata1,2

4. DNA Topoisomerase I Inhibitors: Chemistry, Biology, and Interfacial Inhibition

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