Rational Design and Synthesis of Potent Dibenzazepine Motifs as β-Secretase Inhibitors-Reference-Cited by-同舟云学术

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Rational Design and Synthesis of Potent Dibenzazepine Motifs as β-Secretase Inhibitors

Published:2009-09-29 Issue:20 Volume:52 Page:6484-6488
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Al-Tel Taleb H.¹,Al-Qawasmeh Raed A.²,Schmidt Marco F.³,Al-Aboudi Amal²,Rao Shashidhar N.⁴,Sabri Salim S.¹,Voelter Wolfgang⁵

Affiliation:

1. College of Pharmacy, University of Sharjah, P.O. Box 27272, Sharjah, UAE

2. Department of Chemistry, University of Jordan, Amman 1194, Jordan

3. Leibniz-Institute of Molecular Pharmacology (FMP), Robert-Rössle-Strasse 10, 13125 Berlin, Germany

4. Schrodinger, 120 W. 45th Street, New York, New York 10036

5. Interfakultäres Institut für Biochemie, Eberhard-Karls-Universität Tuebingen, Hoppe-Seyler-Strasse, 72076 Tuebingen, Germany

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm9008482

Reference21 articles.

1. Alzheimer's Disease

2. Views on Amyloid Hypothesis and Secretase Inhibitors for Treating Alzheimers Disease: Progress and Problems

3. cFor online resources and figures about AD, seewww.alz.organdwww.ahaf.org.

4. Age-related cognitive decline, mild cognitive impairment or preclinical Alzheimer's disease?

5. The powerhouse takes control of the cell: Is the mitochondrial permeability transition a viable therapeutic target against neuronal dysfunction and death?

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