3-Arylamino and 3-Alkoxy-nor-β-lapachone Derivatives: Synthesis and Cytotoxicity against Cancer Cell Lines-Reference-Cited by-同舟云学术

3-Arylamino and 3-Alkoxy-nor-β-lapachone Derivatives: Synthesis and Cytotoxicity against Cancer Cell Lines

Published:2009-11-30 Issue:1 Volume:53 Page:504-508
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

da Silva Júnior Eufrânio N.¹,de Deus Clara F.¹,Cavalcanti Bruno C.²,Pessoa Cláudia²,Costa-Lotufo Letícia V.²,Montenegro Raquel C.²,de Moraes Manoel O.²,Pinto Maria do Carmo F. R.³,de Simone Carlos A.⁴⁵,Ferreira Vitor F.⁶,Goulart Marilia O. F.⁴,Andrade Carlos Kleber Z.¹,Pinto Antônio V.³

Affiliation:

1. Instituto de Química, Universidade de Brasília, 70910-970 Brasília, DF, Brazil

2. Departamento de Fisiologia e Farmacologia, Universidade Federal do Ceará, Campus do Porangabussu, 60430-270 Fortaleza, CE, Brazil

3. Núcleo de Pesquisas em Produtos Naturais, UFRJ, P.O. Box 69035, 21941-971, Rio de Janeiro, RJ, Brazil

4. Instituto de Química e Biotecnologia, UFAL, Tabuleiro do Martins, 57072-970 Maceió, AL, Brazil

5. Departamento de Física e Informática, Instituto de Física, USP, 13560-970 São Carlos, SP, Brazil

6. Departamento de Química Orgânica, Instituto de Química, Universidade Federal Fluminense, Campus do Valonguinho, 24020-150 Niterói, RJ, Brazil

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm900865m

Reference22 articles.

1. Electrochemical parameters and techniques in drug development, with an emphasis on quinones and related compounds

2. Antitumoral, antileishmanial and antimalarial activity of pentacyclic 1,4-naphthoquinone derivatives

3. Inhibition of topoisomerase I by naphthoquinone derivatives

4. Synthesis and antimicrobial evaluation of 3-hydrazino-naphthoquinones as analogs of lapachol

5. Ascorbic acid potentiates the cytotoxicity of the naphthoquinone 5-methoxy-3,4-dehydroxanthomegnin

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