1. School of Pharmacy, Shanghai Jiao Tong University, Shanghai 200240, P. R. China, Laboratory of Biocatalysis and Bioprocessing, State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai 200237, P.R. China, Shanghai Highly Integrated Bioprocess Science and Technology Co, Shanghai 200238, P.R. China, and Institute of Biotechnology, Shanghai Jiao Tong University, Shanghai 201101, P.R. China