Ionizable Amino Lipids Distribution and Effects on DSPC/Cholesterol Membranes: Implications for Lipid Nanoparticle Structure-Reference-Cited by-同舟云学术

Ionizable Amino Lipids Distribution and Effects on DSPC/Cholesterol Membranes: Implications for Lipid Nanoparticle Structure

Published:2023-07-27 Issue:31 Volume:127 Page:6928-6939
ISSN:1520-6106
Container-title:The Journal of Physical Chemistry B
language:en
Short-container-title:J. Phys. Chem. B

Author:

Dehghani-Ghahnaviyeh Sepehr¹²,Smith Michael¹,Xia Yan¹,Dousis Athanasios¹,Grossfield Alan³^ORCID,Sur Sreyoshi¹^ORCID

Affiliation:

1. Moderna, Inc., Cambridge, Massachusetts 02139, United States

2. Theoretical and Computational Biophysics Group, NIH Center for Macromolecular Modeling and Bioinformatics, Beckman Institute for Advanced Science and Technology, Department of Biochemistry, and Center for Biophysics and Quantitative Biology, University of Illinois at Urbana−Champaign, Urbana, Illinois 61820, United States

3. Department of Biochemistry and Biophysics, University of Rochester Medical Center, Rochester, New York 14642, United States

Funder

Moderna

Publisher

American Chemical Society (ACS)

Subject

Materials Chemistry,Surfaces, Coatings and Films,Physical and Theoretical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jpcb.3c01296

Reference70 articles.

1. Tools for translation: non-viral materials for therapeutic mRNA delivery

2. mRNA-based therapeutics — developing a new class of drugs