Dehydrogenase Binding Sites Abolish the “Dark” Fraction of NADH: Implication for Metabolic Sensing via FLIM-Reference-Cited by-同舟云学术

Dehydrogenase Binding Sites Abolish the “Dark” Fraction of NADH: Implication for Metabolic Sensing via FLIM

Published:2020-07-13 Issue:31 Volume:124 Page:6721-6727
ISSN:1520-6106
Container-title:The Journal of Physical Chemistry B
language:en
Short-container-title:J. Phys. Chem. B

Author:

Cao Simin¹,Li Haoyang¹,Liu Yangyi¹,Wang Mengyu¹,Zhang Mengjie¹,Zhang Sanjun¹^ORCID,Chen Jinquan¹^ORCID,Xu Jianhua¹^ORCID,Knutson Jay R.²,Brand Ludwig³

Affiliation:

1. State Key Laboratory of Precision Spectroscopy, East China Normal University, Shanghai 200062, China

2. Laboratory for Advanced Microscopy and Biophotonics, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland 20892, United States

3. Department of Biology, Johns Hopkins University, 3400 North Charles Street, Baltimore, Maryland 21218, United States

Funder

National Natural Science Foundation of China

Publisher

American Chemical Society (ACS)

Subject

Materials Chemistry,Surfaces, Coatings and Films,Physical and Theoretical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jpcb.0c04835

Reference46 articles.

1. Imaging Cytosolic NADH-NAD+ Redox State with a Genetically Encoded Fluorescent Biosensor

2. Intracellular Oxidation-Reduction States in Vivo

3. Oxidation-reduction ratio studies of mitochondria in freeze-trapped samples. NADH and flavoprotein fluorescence signals.

4. Metabolic Mapping of MCF10A Human Breast Cells via Multiphoton Fluorescence Lifetime Imaging of the Coenzyme NADH

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