Investigation of the pKa of the Nucleophilic O2′ of the Hairpin Ribozyme
Author:
Affiliation:
1. Department of Chemistry, Yale University, New Haven, Connecticut 06520, United States
2. Department of Chemistry and Biochemistry, Loyola University Chicago, Chicago, Illinois 60660, United States
Funder
Pennsylvania Space Grant Consortium
Loyola University Chicago
National Institute of General Medical Sciences
Extreme Science and Engineering Discovery Environment
Publisher
American Chemical Society (ACS)
Subject
Materials Chemistry,Surfaces, Coatings and Films,Physical and Theoretical Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.jpcb.1c06546
Reference84 articles.
1. Many Activities, One Structure: Functional Plasticity of Ribozyme Folds
2. Ribozyme speed limits
3. An Ontology for Facilitating Discussion of Catalytic Strategies of RNA-Cleaving Enzymes
4. Crystal structure of a hairpin ribozyme–inhibitor complex with implications for catalysis
5. Transition State Stabilization by a Catalytic RNA
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