Probing ATP/ATP-Aptamer or ATP-Aptamer Mutant Complexes by Microscale Thermophoresis and Molecular Dynamics Simulations: Discovery of an ATP-Aptamer Sequence of Superior Binding Properties
Author:
Affiliation:
1. Institute of Chemistry, The Hebrew University of Jerusalem, Jerusalem 91904, Israel
2. Laboratory of Organic Chemistry, Wageningen University & Research, Stippeneng 4, 6708 WE, The Netherlands
Funder
Volkswagen Foundation
Minerva Center for Complex Bio-hybrid Systems
Publisher
American Chemical Society (ACS)
Subject
Materials Chemistry,Surfaces, Coatings and Films,Physical and Theoretical Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.jpcb.8b06802
Reference37 articles.
1. Breitsprecher, D.; Schlinck, N.; Witte, D.; Duhr, S.; Baaske, P.; Schubert, T. Nucleic Acid Aptamers. Methods in Molecular Biology; Mayer, G., Ed. Humana Press: New York, 2016; Vol. 1380, pp 99–111.
2. Trapping of DNA by Thermophoretic Depletion and Convection
3. Thermophoretic Depletion Follows Boltzmann Distribution
4. Why molecules move along a temperature gradient
5. Optical Thermophoresis for Quantifying the Buffer Dependence of Aptamer Binding
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