High-Pressure, Low-Temperature Induced Unfolding and Aggregation of Monoclonal Antibodies: Role of the Fc and Fab Fragments-Reference-Cited by-同舟云学术

High-Pressure, Low-Temperature Induced Unfolding and Aggregation of Monoclonal Antibodies: Role of the Fc and Fab Fragments

Author:

Berger Jordan E.¹^ORCID,Teixeira Susana C. M.¹²,Reed Kaelan³,Razinkov Vladimir I.⁴,Sloey Christopher J.⁴,Qi Wei⁴,Roberts Christopher J.¹^ORCID

Affiliation:

1. Department of Chemical and Biomolecular Engineering, University of Delaware, Newark, Delaware 19716, United States

2. NIST Center for Neutron Research, National Institute of Standards and Technology, Gaithersburg, Maryland 20899, United States

3. PharmBIO Products, W. L. Gore & Associates, Elkton, Maryland 21921, United States

4. Drug Product Technologies, Amgen, Thousand Oaks, California 91320, United States

Funder

NIST Center for Neutron Research

Publisher

American Chemical Society (ACS)

Subject

Materials Chemistry,Surfaces, Coatings and Films,Physical and Theoretical Chemistry

Link

Reference69 articles.

3. Philo, J. S.; Tsutomu, A. Mechanisms of Protein Aggregation. 2010, 1401.

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