Mechanistic Study of Potent Fluorinated EGFR Kinase Inhibitors with a Quinazoline Scaffold against L858R/T790M/C797S Resistance Mutation: Unveiling the Fluorine Substituent Cooperativity Effect on the Inhibitory Activity-Reference-Cited by-同舟云学术

Mechanistic Study of Potent Fluorinated EGFR Kinase Inhibitors with a Quinazoline Scaffold against L858R/T790M/C797S Resistance Mutation: Unveiling the Fluorine Substituent Cooperativity Effect on the Inhibitory Activity

Published:2020-06-30 Issue:28 Volume:124 Page:5813-5824
ISSN:1520-6106
Container-title:The Journal of Physical Chemistry B
language:en
Short-container-title:J. Phys. Chem. B

Author:

Akher Farideh Badichi¹²^ORCID,Farrokhzadeh Abdolkarim³,Ravenscroft Neil²,Kuttel Michelle M.¹^ORCID

Affiliation:

1. Department of Computer Science, University of Cape Town, Cape Town 7701, South Africa

2. Department of Chemistry, University of Cape Town, Cape Town 7700, South Africa

3. School of Chemistry and Physics, University of KwaZulu-Natal, Private Bag X01, Pietermaritzburg 3209, South Africa

Publisher

American Chemical Society (ACS)

Subject

Materials Chemistry,Surfaces, Coatings and Films,Physical and Theoretical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jpcb.0c03440

Reference81 articles.

1. Epidermal growth factor receptor mutations in lung cancer

2. Review of epidermal growth factor receptor biology

3. EGFR exon mutation distribution and outcome in non-small-cell lung cancer: a Portuguese retrospective study

4. The future of adjuvant chemotherapy for resected non-small cell lung cancer

5. Epidermal growth factor receptor (EGFR) signaling in cancer

Cited by 8 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Trifluoromethyl-pyridine carboxylic acid Zn(ii) complexes: isomeric effects on coordination and biological activity;New Journal of Chemistry;2024

2. Binding Thermodynamics of Fourth-Generation EGFR Inhibitors Revealed by Absolute Binding Free Energy Calculations;Journal of Chemical Information and Modeling;2023-12-06

3. Bovine serum albumin binding property of Dy(III) and Tm(III) complexes based on pyridine-2-carboxylic acid;CHINESE J INORG CHEM;2023

4. A multiple detection method for distinguishing gene mutations based on melting curves of extended quenching probes;Heliyon;2022-11

5. Synthesis, Crystal Structure and DNA-Binding Property of a New Cu(II) Complex Based on 4-(Trifluoro-methyl)nicotinic Acid;CHINESE J STRUC CHEM;2022