Mechanism of the Covalent Inhibition of Human Transmembrane Protease Serine 2 as an Original Antiviral Strategy-Reference-Cited by-同舟云学术

Mechanism of the Covalent Inhibition of Human Transmembrane Protease Serine 2 as an Original Antiviral Strategy

Published:2023-07-10 Issue:28 Volume:127 Page:6287-6295
ISSN:1520-6106
Container-title:The Journal of Physical Chemistry B
language:en
Short-container-title:J. Phys. Chem. B

Author:

Spinello Angelo¹^ORCID,D’Anna Luisa¹^ORCID,Bignon Emmanuelle²^ORCID,Miclot Tom¹²,Grandemange Stéphanie³,Terenzi Alessio¹^ORCID,Barone Giampaolo¹^ORCID,Barbault Florent⁴^ORCID,Monari Antonio⁴^ORCID

Affiliation:

1. Department of Biological, Chemical and Pharmaceutical Sciences, University of Palermo, 90126 Palermo, Italy

2. Université de Lorraine and CNRS, UMR 7019 LPCT, F-54000 Nancy, France

3. Université de Lorraine and CNRS, UMR 7039 CRAN, F-54000 Nancy, France

4. Université Paris Cité and CNRS, ITODYS, F-75006 Paris, France

Funder

Commissariat G?n?ral ? l'Investissement

Agence Nationale de la Recherche

Minist?re de l'Enseignement Sup?rieur et de la Recherche (Luxembourg)

Centre National de la Recherche Scientifique

Ministero dell'Universit? e della Ricerca

Publisher

American Chemical Society (ACS)

Subject

Materials Chemistry,Surfaces, Coatings and Films,Physical and Theoretical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jpcb.3c02910

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2. Matriptase and MET are prominently expressed at the site of bone metastasis in renal cell carcinoma: immunohistochemical analysis

3. TMPRSS2 and ADAM17 Cleave ACE2 Differentially and Only Proteolysis by TMPRSS2 Augments Entry Driven by the Severe Acute Respiratory Syndrome Coronavirus Spike Protein

4. Epithelial Integrity Is Maintained by a Matriptase-Dependent Proteolytic Pathway

5. TMPRSS2 Serves as a Prognostic Biomarker and Correlated With Immune Infiltrates in Breast Invasive Cancer and Lung Adenocarcinoma

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