Real-Time Monitoring of the Multistate Conformational Dynamics of Polypurine Reverse Hoogsteen Hairpin To Capture Their Triplex-Affinity for Gene Silencing by smFRET Microspectroscopy
Author:
Affiliation:
1. Single-Molecule Biophysics Lab, Chemical Sciences Division, Saha Institute of Nuclear Physics, HBNI Mumbai, 1/AF Bidhannagar, Kolkata 700064, India
Funder
Department of Atomic Energy, Government of India
Science and Engineering Research Board
Publisher
American Chemical Society (ACS)
Subject
Materials Chemistry,Surfaces, Coatings and Films,Physical and Theoretical Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.jpcb.0c05493
Reference69 articles.
1. Strand Displacement of Double-Stranded DNA by Triplex-Forming Antiparallel Purine-Hairpins
2. Properties of triple helices formed by parallel-stranded hairpins containing 8-aminopurines
3. Initiation of DNA Replication by a Third Parallel DNA Strand Bound in a Triple-Helix Manner Leads to Strand Invasion
4. Gene targeting via triple-helix formation
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1. From Ensemble FRET to Single-Molecule Imaging: Monitoring Individual Cellular Machinery in Action;Optical Spectroscopic and Microscopic Techniques;2022
2. Decoding the Structural Dynamics and Conformational Alternations of DNA Secondary Structures by Single-Molecule FRET Microspectroscopy;Frontiers in Molecular Biosciences;2021-09-03
3. Nucleic acids therapeutics using PolyPurine Reverse Hoogsteen hairpins;Biochemical Pharmacology;2021-07
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