Comparative Protein Structural Network Analysis Reveals C-Terminal Tail Phosphorylation Structural Communication Fingerprint in <i>PTEN</i>-Associated Mutations in Autism and Cancer-Reference-Cited by-同舟云学术

Comparative Protein Structural Network Analysis Reveals C-Terminal Tail Phosphorylation Structural Communication Fingerprint in PTEN-Associated Mutations in Autism and Cancer

Published:2023-01-10 Issue:3 Volume:127 Page:634-647
ISSN:1520-6106
Container-title:The Journal of Physical Chemistry B
language:en
Short-container-title:J. Phys. Chem. B

Author:

Smith Iris N.¹^ORCID,Dawson Jennifer E.¹^ORCID,Eng Charis¹²³⁴⁵^ORCID

Affiliation:

1. Genomic Medicine Institute, Lerner Research Institute, Cleveland Clinic, 9500 Euclid Avenue, NE-50, Cleveland, Ohio44195, United States

2. Cleveland Clinic Lerner College of Medicine, Case Western Reserve University, 9500 Euclid Avenue, Cleveland, Ohio44195, United States

3. Case Comprehensive Cancer Center, Case Western Reserve University School of Medicine, 10900 Euclid Avenue, Cleveland, Ohio44106, United States

4. Taussig Cancer Institute, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, Ohio44195, United States

5. Department of Genetics and Genome Sciences, Case Western Reserve University School of Medicine, 10900 Euclid Avenue, Cleveland, Ohio44106, United States

Funder

National Cancer Institute

Ambrose Monell Foundation

National Institute of General Medical Sciences

Ohio Supercomputing Center

Publisher

American Chemical Society (ACS)

Subject

Materials Chemistry,Surfaces, Coatings and Films,Physical and Theoretical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jpcb.2c06776

Reference65 articles.

1. Lifetime Cancer Risks in Individuals with Germline PTEN Mutations

2. Subset of individuals with autism spectrum disorders and extreme macrocephaly associated with germline PTEN tumour suppressor gene mutations

3. PTEN: One Gene, Many Syndromes

4. A Clinical Scoring System for Selection of Patients for PTEN Mutation Testing Is Proposed on the Basis of a Prospective Study of 3042 Probands

5. The Clinical Spectrum of PTEN Mutations

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