Allosteric Mechanism of Human Mitochondrial Phenylalanyl-tRNA Synthetase: An Atomistic MD Simulation and a Mutual Information-Based Network Study
Author:
Affiliation:
1. Faculty of Environmental and Life Sciences, Beijing University of Technology, Beijing 100124, China
Funder
National Natural Science Foundation of China
Publisher
American Chemical Society (ACS)
Subject
Materials Chemistry,Surfaces, Coatings and Films,Physical and Theoretical Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.jpcb.1c03228
Reference38 articles.
1. Aminoacyl-tRNA Synthesis
2. Aminoacyl tRNA synthetases and their connections to disease
3. Crystal Structure of Human Mitochondrial PheRS Complexed with tRNAPhe in the Active “Open” State
4. Kinetic and structural changes in H smt PheRS, induced by pathogenic mutations in human FARS 2
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