Computational Screening for mAb Colloidal Stability with Coarse-Grained, Molecular-Scale Simulations-Reference-Cited by-同舟云学术

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Computational Screening for mAb Colloidal Stability with Coarse-Grained, Molecular-Scale Simulations

Published:2024-02-05 Issue:6 Volume:128 Page:1515-1526
ISSN:1520-6106
Container-title:The Journal of Physical Chemistry B
language:en
Short-container-title:J. Phys. Chem. B

Author:

Janke J. Joel¹,Starr Charles G.¹,Kingsbury Jonathan S.¹^ORCID,Furtmann Norbert²,Roberts Christopher J.³^ORCID,Calero-Rubio Cesar¹^ORCID

Affiliation:

1. Biologics Drug Product Development and Manufacturing, Sanofi, Framingham, Massachusetts 01701, United States

2. Large Molecules Research Platform, Sanofi-Aventis Deutschland GmbH, Frankfurt 65926, Germany

3. Department of Chemical and Biomolecular Engineering, University of Delaware, Newark, Delaware 19716, United States

Funder

Sanofi

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jpcb.3c05303

Reference60 articles.

1. The pharmacology and therapeutic applications of monoclonal antibodies

2. Immune- and Non-Immune-Mediated Adverse Effects of Monoclonal Antibody Therapy: A Survey of 110 Approved Antibodies

3. FDA approves 100th monoclonal antibody product

4. US FDA-approved therapeutic antibodies with high-concentration formulation: summaries and perspectives

5. Therapeutic protein aggregation: mechanisms, design, and control

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1. Predicting blood–brain barrier permeability of molecules with a large language model and machine learning;Scientific Reports;2024-07-09

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