Detection of Drug Binding to a Target Protein Using EVV 2DIR Spectroscopy-Reference-Cited by-同舟云学术

Detection of Drug Binding to a Target Protein Using EVV 2DIR Spectroscopy

Published:2019-03-08 Issue:17 Volume:123 Page:3598-3606
ISSN:1520-6106
Container-title:The Journal of Physical Chemistry B
language:en
Short-container-title:J. Phys. Chem. B

Author:

Sowley Hugh,Liu ZhiQiang¹^ORCID,Davies Julia^ORCID,Peach Robert^ORCID,Guo Rui^ORCID,Sim Sophie^ORCID,Long FengQin¹,Holdgate Geoffrey²,Willison Keith,Zhuang Wei¹,Klug David R.^ORCID

Affiliation:

1. State Key Laboratory of Structural Chemistry, Fujian Institute of Research on Structure of Matters, CAS, Fuzhou 350002, P. R. China

2. Hit Discovery, Discovery Sciences, IMED Biotech Unit, AstraZeneca, Macclesfield SK10 2NA, U.K.

Funder

National Natural Science Foundation of China

Biotechnology and Biological Sciences Research Council

Engineering and Physical Sciences Research Council

Ministry of Science and Technology of the People's Republic of China

Rosalind Franklin Institute

Publisher

American Chemical Society (ACS)

Subject

Materials Chemistry,Surfaces, Coatings and Films,Physical and Theoretical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jpcb.9b00501

Reference33 articles.

1. Biophysics in drug discovery: impact, challenges and opportunities

2. NMR in drug discovery: A practical guide to identification and validation of ligands interacting with biological macromolecules

3. Cryo-electron microscopy and X-ray crystallography: complementary approaches to structural biology and drug discovery

4. Missing strings of residues in protein crystal structures

5. Characterization of Ligand Binding by Saturation Transfer Difference NMR Spectroscopy

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