Synthesis and In Vitro Evaluation of Imidazo[1,2-b]pyridazines as Ligands for β-Amyloid Plaques
Author:
Affiliation:
1. Department of Radiology
2. Institute for Degenerative Disorders, New Haven, Connecticut 06510
3. Center for Neurodegenerative Disease and Department of Neurology
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Drug Discovery,Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/ml100005j
Reference26 articles.
1. Alzheimer's Disease: Genes, Proteins, and Therapy
2. The Amyloid Hypothesis of Alzheimer's Disease: Progress and Problems on the Road to Therapeutics
3. Emerging β-Amyloid Therapies for the Treatment of Alzheimers Disease
4. Novel Therapeutic Approach for the Treatment of Alzheimer's Disease by Peripheral Administration of Agents with an Affinity to β-Amyloid
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2. Imidazo[1,2-b]pyridazine as privileged scaffold in medicinal chemistry: An extensive review;European Journal of Medicinal Chemistry;2021-12
3. Design, synthesis and anticancer activity of sulfenylated imidazo-fused heterocycles;Bioorganic & Medicinal Chemistry Letters;2021-10
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5. Discovery of Diphenoxy Derivatives with Flexible Linkers as Ligands for β-Amyloid Plaques;Molecular Pharmaceutics;2020-08-26
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