{(1R,2R,4R)-4-Methyl-1,2-cyclohexanediamine}oxalatoplatinum(II): A Novel Enantiomerically Pure Oxaliplatin Derivative Showing Improved Anticancer Activity in Vivo-Reference-Cited by-同舟云学术

{(1R,2R,4R)-4-Methyl-1,2-cyclohexanediamine}oxalatoplatinum(II): A Novel Enantiomerically Pure Oxaliplatin Derivative Showing Improved Anticancer Activity in Vivo

Published:2010-10-01 Issue:20 Volume:53 Page:7356-7364
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Abramkin Sergey A.¹,Jungwirth Ute²,Valiahdi Seied M.¹,Dworak Claudia¹,Habala Ladislav¹,Meelich Kristof¹,Berger Walter²³,Jakupec Michael A.¹,Hartinger Christian G.¹,Nazarov Alexey A.⁴,Galanski Markus¹,Keppler Bernhard K.¹³

Affiliation:

1. University of Vienna, Institute of Inorganic Chemistry, Währinger Strasse 42, A-1090 Vienna, Austria

2. Department of Medicine I, Institute of Cancer Research, Medical University of Vienna, Borschkegasse 8a, A-1090 Vienna, Austria

3. Research Platform “Translational Cancer Therapy Research” University of Vienna, Währinger Strasse 42, A-1090 Vienna, Austria

4. Institut des Sciences et Ingénierie Chimiques, Ecole Polytechnique Fédérale de Lausanne (EPFL), CH-1015 Lausanne, Switzerland

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm100953c

Reference33 articles.

1. Cisplatin

2. Inhibition of Cell Division in Escherichia coli by Electrolysis Products from a Platinum Electrode

3. Platinum Complexes for the Treatment of Cancer

4. Antitumor activity of 1,2-diaminocyclohexaneplatinum complexes against Sarcoma-180 ascites form

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