Site-Directed Mutagenesis of the Sterol Methyl Transferase Active Site from Saccharomyces cerevisiae Results in Formation of Novel 24-Ethyl Sterols

Author:

Nes W. David1,McCourt Brian S.1,Marshall Julie A.1,Ma Jianzhong1,Dennis Allen L.1,Lopez Monica1,Li Haoxia1,He Ling1

Affiliation:

1. Department of Chemistry and Biochemistry, Texas Tech University, Lubbock, Texas 79409

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry

Reference51 articles.

1. (a) Janssen, G. G.; Kalinowska, K.; Norton, R. A.; Nes, W. D. InPhysiology andBiochemistry of Sterols; Patterson, G. W., Nes, W. D., Eds.; American Oil Chemists' Society Press:  Champaign, 1992; pp 83−117.

2. (b) Nes, W. R.; McKean, M. L.Biochemistry of Steroids and Other Isopentenoids;University Park Press:  Baltimore, 1977; pp 325−550.

3. Some problems concerning biological C-alkylation reactions and phytosterol biosynthesis

4. (d) Akihisa, T.; Kokke, W. C. M. C.; Tamura, T. InPhysiology and Biochemistry of Sterols; Patterson, G. W., Nes, W. D., Eds.; American Oil Chemists' Society Press:  Champaign, 1992; pp 172−228.

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