The Development of a Large-Scale Synthesis of Matrix Metalloproteinase Inhibitor, ABT-518-Reference-Cited by-同舟云学术

The Development of a Large-Scale Synthesis of Matrix Metalloproteinase Inhibitor, ABT-518

Published:2002-05-01 Issue:3 Volume:6 Page:329-335
ISSN:1083-6160
Container-title:Organic Process Research & Development
language:en
Short-container-title:Org. Process Res. Dev.

Author:

Chang Sou-Jen¹,Fernando Dilinie¹,Fickes Michael¹,Gupta Ashok K.¹,Hill David R.¹,McDermott Todd¹,Parekh Shyamal¹,Tian Zhenping¹,Wittenberger Steven J.¹

Affiliation:

1. Abbott Laboratories, Global Pharmaceutical R&D, Process R&D, 1401 Sheridan Road, D-R450, Building R-8, North Chicago, Illinois 60064-4000, U.S.A.

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/op025525l

Reference8 articles.

1. Phenoxyphenyl Sulfone N-Formylhydroxylamines (Retrohydroxamates) as Potent, Selective, Orally Bioavailable Matrix Metalloproteinase Inhibitors

2. Matrix metalloproteinases in cancer invasion, metastasis and angiogenesis

3. The decomposition of17, a lithium ester enolate related to8b, via a β-elimination mechanism to form acetone at temperatures ≥−50 °C has been reported. Leighton J. L. Ph.D. Thesis, Harvard University, Cambridge, MA, 1994.

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