Bridging Disulfides for Stable and Defined Antibody Drug Conjugates-Reference-Cited by-同舟云学术

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Bridging Disulfides for Stable and Defined Antibody Drug Conjugates

Published:2014-05-23 Issue:6 Volume:25 Page:1124-1136
ISSN:1043-1802
Container-title:Bioconjugate Chemistry
language:en
Short-container-title:Bioconjugate Chem.

Author:

Badescu George¹,Bryant Penny¹,Bird Matthew¹,Henseleit Korinna¹,Swierkosz Julia¹,Parekh Vimal¹,Tommasi Rita¹,Pawlisz Estera¹,Jurlewicz Kosma¹,Farys Monika¹,Camper Nicolas¹,Sheng XiaoBo¹,Fisher Martin¹,Grygorash Ruslan¹,Kyle Andrew¹,Abhilash Amrita¹,Frigerio Mark¹,Edwards Jeff¹,Godwin Antony¹

Affiliation:

1. PolyTherics Ltd, The London Bioscience Innovation Centre, 2 Royal College Street, London NW1 0NH, United Kingdom

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Pharmaceutical Science,Pharmacology,Biomedical Engineering,Bioengineering,Biotechnology

Link

https://pubs.acs.org/doi/pdf/10.1021/bc500148x

Reference40 articles.

1. Targeting HER2-Positive Breast Cancer with Trastuzumab-DM1, an Antibody–Cytotoxic Drug Conjugate

2. Structural characterization of the maytansinoid-monoclonal antibody immunoconjugate, huN901-DM1, by mass spectrometry

3. Protease-Mediated Fragmentation of p-Amidobenzyl Ethers: A New Strategy for the Activation of Anticancer Prodrugs

4. Reduction−Alkylation Strategies for the Modification of Specific Monoclonal Antibody Disulfides

5. Development of potent monoclonal antibody auristatin conjugates for cancer therapy

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