Synthesis, Molecular Modeling, and Opioid Receptor Affinity of 9,10-Diazatricyclo[4.2.1.12,5]decanes and 2,7-Diazatricyclo[4.4.0.03,8]decanes Structurally Related to 3,8-Diazabicyclo[3.2.1]octanes-Reference-Cited by-同舟云学术

Synthesis, Molecular Modeling, and Opioid Receptor Affinity of 9,10-Diazatricyclo[4.2.1.12,5]decanes and 2,7-Diazatricyclo[4.4.0.03,8]decanes Structurally Related to 3,8-Diazabicyclo[3.2.1]octanes

Published:2000-05-12 Issue:11 Volume:43 Page:2115-2123
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Vianello Paola¹,Albinati Alberto¹,Pinna Gerardo A.¹,Lavecchia Antonio¹,Marinelli Luciana¹,Borea Pier Andrea¹,Gessi Stefania¹,Fadda Paola¹,Tronci Silvia¹,Cignarella Giorgio¹

Affiliation:

1. Istituto di Chimica Farmaceutica e Tossicologica, Viale Abruzzi 42, 20131 Milano, Italy, Dipartimento Farmaco Chimico Tossicologico, Via Muroni 23/A, 07100 Sassari, Italy, Dipartimento di Chimica Farmaceutica e Tossicologica, Università di Napoli “Federico II”, Via D. Montesano 49, 80131 Napoli, Italy, Dipartimento di Medicina Clinica e Sperimentale, Via Fossato di Mortara 19, 44100 Ferrara, Italy, and Dipartimento di Neuroscienze, Via Porcell 4, 09100 Cagliari, Italy

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm991140q

Reference32 articles.

1. The Synthesis of 3,8-Diazabicyclo[3.2.1]octane and Some of Its N-Substituted Derivatives

2. Thermal and chemical intramolecular N → N acyl-migration in 8-acyl-3, 8-diazabicyclo[3.2.1]octanes

3. Bicyclic Homologs of Piperazine. VII.1 Synthesis and Analgesic Activity of 3-Aralkenyl-8-propionyl-3,8-diazabicyclo[3.2.1]octanes

4. Interaction of 3,8-diazabicyclo (3.2.1) octanes with mu and delta opioid receptors

5. Antinociceptive action of DBO 17 and DBO 11 in mice: two 3,8 diazabicyclo (3.2.1.) octane derivates with selective μ opioid receptor affinity

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