Sulfonate Derivatives of Naphtho[2,3-b]thiophen-4(9H)-one and 9(10H)-Anthracenone as Highly Active Antimicrotubule Agents. Synthesis, Antiproliferative Activity, and Inhibition of Tubulin Polymerization-Reference-Cited by-同舟云学术

Sulfonate Derivatives of Naphtho[2,3-b]thiophen-4(9H)-one and 9(10H)-Anthracenone as Highly Active Antimicrotubule Agents. Synthesis, Antiproliferative Activity, and Inhibition of Tubulin Polymerization

Published:2007-10-31 Issue:24 Volume:50 Page:6059-6066
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Zuse Anne¹,Schmidt Peter¹,Baasner Silke¹,Böhm Konrad J.¹,Müller Klaus¹,Gerlach Matthias¹,Günther Eckhard G.¹,Unger Eberhard¹,Prinz Helge¹

Affiliation:

1. Department of Biochemistry and Medical Genetics, Manitoba Institute of Cell Biology, CancerCare Manitoba, ON6010-675 McDermot Avenue, Winnipeg, Canada, Institute of Pharmaceutical and Medicinal Chemistry, Westphalian Wilhelms-University, Hittorfstrasse 58-62, D-48149 Münster, Germany, Aeterna Zentaris, Weismüllerstrasse 50, D-60314 Frankfurt, Germany, and Leibniz Institute for Age Research−Fritz Lipmann Institute (FLI), Beutenbergstrasse 11, D-07745 Jena, Germany

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm0708984

Reference40 articles.

1. Understanding microtubule dynamics for improved cancer therapy

2. Review: Tubulin Function, Action of Antitubulin Drugs, and New Drug Development

3. Isolation and structure of the strong cell growth and tubulin inhibitor combretastatin A-4

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