Understanding Programming of Fungal Iterative Polyketide Synthases: The Biochemical Basis for Regioselectivity by the Methyltransferase Domain in the Lovastatin Megasynthase-Reference-Cited by-同舟云学术

Understanding Programming of Fungal Iterative Polyketide Synthases: The Biochemical Basis for Regioselectivity by the Methyltransferase Domain in the Lovastatin Megasynthase

Published:2015-12-10 Issue:50 Volume:137 Page:15688-15691
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

Cacho Ralph A.¹,Thuss Justin²,Xu Wei¹,Sanichar Randy²,Gao Zhizeng²,Nguyen Allison¹,Vederas John C.²,Tang Yi¹

Affiliation:

1. Department of Chemical and Biomolecular Engineering, Department of Chemistry and Biochemistry, University of California, Los Angeles, California 90095, United States

2. Department of Chemistry, University of Alberta, Edmonton, AB T6G 2G2, Canada

Funder

National Institute of General Medical Sciences

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Link

https://pubs.acs.org/doi/pdf/10.1021/jacs.5b11814

Reference24 articles.

1. Navigating the Fungal Polyketide Chemical Space: From Genes to Molecules

2. Polyketides, proteins and genes in fungi: programmed nano-machines begin to reveal their secrets