1. Cross-Sector Review of Drivers and Available 3Rs Approaches for Acute Systemic Toxicity Testing
2. OECD. OECD Guideline for the Testing of Chemicals. No.
423: Acute Oral Toxicity ─ Acute Toxic Class Method, 14pp; Organisation for Economic Co-Operation and Development: Paris, France, 2001. Https://Www.Oecd.Org/Chemicalsafety/Risk-Assessment/1948378.Pdf.
3. ICH
Expert Working Group. ICH Topic M3
(R2): Non-clinical Safety Studies
for the Conduct of Human Clinical Trials and Marketing Authorization
for Pharmaceuticals, Step 4, June 2009, CPMP/ICH/286/95, 25pp; European Medicines Agency: London, UK, 2009. Https://Database.Ich.Org/Sites/Default/Files/M3_R2__Guideline.Pdf.
4. Evaluation of Assay Central Machine Learning Models for Rat Acute Oral Toxicity Prediction