Lipid Modulation of a Class B GPCR: Elucidating the Modulatory Role of PI(4,5)P<sub>2</sub> Lipids-Reference-Cited by-同舟云学术

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Lipid Modulation of a Class B GPCR: Elucidating the Modulatory Role of PI(4,5)P₂ Lipids

Published:2022-08-29 Issue:24 Volume:62 Page:6788-6802
ISSN:1549-9596
Container-title:Journal of Chemical Information and Modeling
language:en
Short-container-title:J. Chem. Inf. Model.

Author:

Kjølbye Lisbeth R.¹²,Sørensen Lars²,Yan Jun²,Berglund Nils A.¹,Ferkinghoff-Borg Jesper²,Robinson Carol V.³^ORCID,Schiøtt Birgit¹⁴^ORCID

Affiliation:

1. Department of Chemistry, Aarhus University, Langelandsgade 140, 8000 Aarhus C, Denmark

2. Novo Nordisk A/S, Novo Nordisk Park 1, 2760 Måløv, Denmark

3. Department of Chemistry, University of Oxford, South Parks Road, Oxford OX1 3QZ, United Kingdom

4. Interdisciplinary Nanoscience Center, Aarhus University, Gustav Wieds vej 14, 8000 Aarhus C, Denmark

Funder

Novo Nordisk Fonden

Innovationsfonden

Publisher

American Chemical Society (ACS)

Subject

Library and Information Sciences,Computer Science Applications,General Chemical Engineering,General Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jcim.2c00635

Reference89 articles.

1. Drugging Membrane Protein Interactions

2. PtdIns(4,5)P2 stabilizes active states of GPCRs and enhances selectivity of G-protein coupling

3. State-dependent Lipid Interactions with the A2a Receptor Revealed by MD Simulations Using In Vivo-Mimetic Membranes

4. Targeting the glucagon receptor family for diabetes and obesity therapy

5. Insights into the structure of class B GPCRs

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2. Cholesterol Dependence of the Conformational Changes in Metabotropic Glutamate Receptor 1;2024-04-20

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