Development and Validation of a Computational Model Ensemble for the Early Detection of BCRP/ABCG2 Substrates during the Drug Design Stage-Reference-Cited by-同舟云学术

Development and Validation of a Computational Model Ensemble for the Early Detection of BCRP/ABCG2 Substrates during the Drug Design Stage

Published:2017-08-08 Issue:8 Volume:57 Page:1868-1880
ISSN:1549-9596
Container-title:Journal of Chemical Information and Modeling
language:en
Short-container-title:J. Chem. Inf. Model.

Author:

Gantner Melisa E.¹^ORCID,Peroni Roxana N.²,Morales Juan F.¹,Villalba María L.¹,Ruiz María E.¹,Talevi Alan¹

Affiliation:

1. Laboratorio de Investigación y Desarrollo de Bioactivos (LIDeB), Departamento de Ciencias Biológicas, Facultad de Ciencias Exactas, Universidad Nacional de La Plata (UNLP) − Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), La Plata, B1900AJI Buenos Aires, Argentina

2. Instituto de Investigaciones Farmacológicas (ININFA UBA-CONICET), Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, Junín 956 5°, 1113 Ciudad Autónoma de Buenos Aires, Argentina

Funder

Consejo Nacional de Investigaciones Cient?ficas y T?cnicas

Agencia Nacional de Promoci?n Cient?fica y Tecnol?gica

Universidad Nacional de La Plata

Publisher

American Chemical Society (ACS)

Subject

Library and Information Sciences,Computer Science Applications,General Chemical Engineering,General Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jcim.7b00016

Reference95 articles.

1. Introduction: What is Multidrug Resistance?