Modeling the Effect of Hydrophobicity on the Passive Permeation of Solutes across a Bacterial Model Membrane-Reference-Cited by-同舟云学术

Modeling the Effect of Hydrophobicity on the Passive Permeation of Solutes across a Bacterial Model Membrane

Published:2022-10-10 Issue:20 Volume:62 Page:5023-5033
ISSN:1549-9596
Container-title:Journal of Chemical Information and Modeling
language:en
Short-container-title:J. Chem. Inf. Model.

Author:

Sousa Carla F.¹²^ORCID,Kamal Mohamed A.M.²³,Richter Robert²,Elamaldeniya Kalanika²⁴,Hartmann Rolf W.³⁵⁶,Empting Martin³⁷⁵,Lehr Claus-Michael²³^ORCID,Kalinina Olga V.¹⁴⁸

Affiliation:

1. Drug Bioinformatics Group, Helmholtz Centre for Infection Research (HZI), Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Saarbrücken66123, Germany

2. Department of Biological Barriers and Drug Delivery, Helmholtz Centre for Infection Research (HZI), Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Saarbrücken66123, Germany

3. Department of Pharmacy, Saarland University, Saarbrücken66123, Germany

4. Center for Bioinformatics, Saarland University, Saarbrücken66123, Germany

5. German Centre for Infection Research (DZIF) Partner Site Hannover-Braunschweig, Saarbrücken66123, Germany

6. Department of Drug Design and Optimization, Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Helmholtz Centre for Infection Research (HZI), Saarbrücken66123, Germany

7. Antiviral & Antivirulence Drugs Group, Helmholtz Centre for Infection Research (HZI), Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Saarbrücken66123, Germany

8. Medical Faculty, Saarland University, Homburg66421, Germany

Funder

Klaus Faber Foundation

Friendz of HZI

Publisher

American Chemical Society (ACS)

Subject

Library and Information Sciences,Computer Science Applications,General Chemical Engineering,General Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jcim.2c00767

Reference66 articles.

1. Carrier-mediated cellular uptake of pharmaceutical drugs: an exception or the rule?