Characterization of Hydrophilic α-Helical Hot Spots on the Protein–Protein Interaction Interfaces for the Design of α-Helix Mimetics-Reference-Cited by-同舟云学术

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Characterization of Hydrophilic α-Helical Hot Spots on the Protein–Protein Interaction Interfaces for the Design of α-Helix Mimetics

Published:2022-04-06 Issue:8 Volume:62 Page:1873-1890
ISSN:1549-9596
Container-title:Journal of Chemical Information and Modeling
language:en
Short-container-title:J. Chem. Inf. Model.

Author:

Wang Zhen¹²,Ji Haitao¹²^ORCID

Affiliation:

1. Drug Discovery Department, H. Lee Moffitt Cancer Center & Research Institute, 12902 Magnolia Drive, Tampa, Florida 33612−9497, United States

2. Departments of Chemistry and Oncologic Sciences, University of South Florida, Tampa, Florida 33620−9497, United States

Funder

National Cancer Institute

Publisher

American Chemical Society (ACS)

Subject

Library and Information Sciences,Computer Science Applications,General Chemical Engineering,General Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jcim.1c01556

Reference92 articles.

1. Hydrocarbon-Stapled Peptides: Principles, Practice, and Progress

2. An All-Hydrocarbon Cross-Linking System for Enhancing the Helicity and Metabolic Stability of Peptides

3. The Hydrogen Bond Mimic Approach: Solid-Phase Synthesis of a Peptide Stabilized as an α-Helix with a Hydrazone Link

4. Activation of Apoptosis in Vivo by a Hydrocarbon-Stapled BH3 Helix

5. A Perfluoroaryl-Cysteine SNAr Chemistry Approach to Unprotected Peptide Stapling

Cited by 4 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. CSSP-2.0: A refined consensus method for accurate protein secondary structure prediction;Computational Biology and Chemistry;2024-10

2. Deformation and crack prediction of CORC cable induced by Poisson effect: Theoretical modeling and experimental validation;Engineering Fracture Mechanics;2023-11

3. Common Structural Features of Hydrophobic α-Helical Hot Spots: Insights for the Design of Novel α-Helix Mimetics;ACS Medicinal Chemistry Letters;2022-09-14

4. Fragment hopping protocol for the design of small-molecule protein–protein interaction inhibitors;Bioorganic & Medicinal Chemistry;2022-09

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