Discovery of Anticancer Hybrid Molecules by Supervised Machine Learning Models and <i>in Vitro</i> Validation in Drug Resistant Chronic Myeloid Leukemia Cells-Reference-Cited by-同舟云学术

Discovery of Anticancer Hybrid Molecules by Supervised Machine Learning Models and in Vitro Validation in Drug Resistant Chronic Myeloid Leukemia Cells

Published:2022-02-17 Issue:4 Volume:62 Page:1126-1146
ISSN:1549-9596
Container-title:Journal of Chemical Information and Modeling
language:en
Short-container-title:J. Chem. Inf. Model.

Author:

Melge Anu R¹,Parate Shraddha¹^ORCID,Pavithran Keechilat²,Koyakutty Manzoor¹^ORCID,Mohan C Gopi¹^ORCID

Affiliation:

1. Centre for Nanosciences and Molecular Medicine, Amrita Vishwa Vidyapeetham, Ponekkara, Kochi, Kerala 682041, India

2. Department of Oncology, Amrita Institute of Medical Sciences and Research Centre, Amrita Vishwa Vidyapeetham, Ponekkara, Kochi, Kerala 682041, India

Funder

Council of Scientific and Industrial Research

Publisher

American Chemical Society (ACS)

Subject

Library and Information Sciences,Computer Science Applications,General Chemical Engineering,General Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jcim.1c01554

Reference49 articles.

1. Epigenetic mechanisms underlying the therapeutic effects of HDAC inhibitors in chronic myeloid leukemia

2. Imatinib—A New Tyrosine Kinase Inhibitor for First-Line Treatment of Chronic Myeloid Leukemia in 2015

3. Treatment outcome in a population-based, ‘real-world’ cohort of patients with chronic myeloid leukemia

4. Polypharmacology: Challenges and Opportunities in Drug Discovery

Cited by 9 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Escin’s phytochemistry and pharmacy: biosynthesis, chemistry, synergism and novel activities;Phytochemistry Reviews;2024-07-16

2. WITHDRAWN: Elucidating the molecular mechanism of phytochemicals against Parkinson’s disease through an integrated systems biology and molecular modeling approach;2024-05-14

3. Role of Artificial Intelligence in Revolutionizing Drug Discovery;Fundamental Research;2024-05

4. From understanding diseases to drug design: can artificial intelligence bridge the gap?;Artificial Intelligence Review;2024-03-11

5. Artificial Intelligence-Based Management of Adult Chronic Myeloid Leukemia: Where Are We and Where Are We Going?;Cancers;2024-02-20