Understanding the Binding Specificity of G-Protein Coupled Receptors toward G-Proteins and Arrestins: Application to the Dopamine Receptor Family-Reference-Cited by-同舟云学术

Understanding the Binding Specificity of G-Protein Coupled Receptors toward G-Proteins and Arrestins: Application to the Dopamine Receptor Family

Published:2020-07-21 Issue:8 Volume:60 Page:3969-3984
ISSN:1549-9596
Container-title:Journal of Chemical Information and Modeling
language:en
Short-container-title:J. Chem. Inf. Model.

Author:

Preto A. J.¹²³^ORCID,Barreto Carlos A. V.¹²³^ORCID,Baptista Salete J.¹²⁴,Almeida José Guilherme de¹⁵,Lemos Agostinho¹⁶^ORCID,Melo André⁷,Cordeiro M. Nátalia D. S.⁷^ORCID,Kurkcuoglu Zeynep⁸,Melo Rita¹²⁴^ORCID,Moreira Irina S.¹²⁹^ORCID

Affiliation:

1. CNC - Center for Neuroscience and Cell Biology, University of Coimbra, Faculty of Medicine, Pólo I, 1st floor, 3004-504 Coimbra, Portugal

2. University of Coimbra, Center for Innovative Biomedicine and Biotechnology, Faculty of Medicine, Pólo I, 1st floor, 3004-504 Coimbra, Portugal

3. Institute for Interdisciplinary Research, University of Coimbra, Casa Costa Alemão - Pólo II | Rua Dom Francisco de Lemos, 3030-789 Coimbra, Portugal

4. Centro de Ciências e Tecnologias Nucleares, Instituto Superior Técnico, Universidade de Lisboa, Estrada Nacional 10, ao Km 139,7, 2695-066 Bobadela, Portugal

5. European Bioinformatics Institute EMBL-EBI, Hinxton, Cambridgeshire CB10 1SD, United Kingdom

6. GIGA Cyclotron Research Centre In Vivo Imaging, University of Liège, Bâtiment B30, Allée du 6 Août, 8, 4000 Liège, Belgium

7. REQUIMTE/LAQV, Departamento de Química e Bioquímica, Faculdade de Ciências da Universidade do Porto, Rua Campo Alegre 687, s/n, 4169-007 Porto, Portugal

8. Bijvoet Center for Biomolecular Research, Faculty of Science − Chemistry, Utrecht University, Padualaan 8, 3584 CH Utrecht, The Netherlands

9. Department of Life Sciences, University of Coimbra, Colégio de S. Bento, Calçada Martim de Freitas, 3000-456 Coimbra, Portugal

Funder

European Regional Development Fund

European Social Fund

Funda??o para a Ci?ncia e a Tecnologia

Publisher

American Chemical Society (ACS)

Subject

Library and Information Sciences,Computer Science Applications,General Chemical Engineering,General Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jcim.0c00371

Reference86 articles.

1. A GIPC1-Palmitate Switch Modulates Dopamine Drd3 Receptor Trafficking and Signaling

2. A mechanistic role of Helix 8 in GPCRs: Computational modeling of the dopamine D2 receptor interaction with the GIPC1–PDZ-domain

3. G protein coupled receptor structure and activation

4. G-protein-coupled receptor structure, ligand binding and activation as studied by solid-state NMR spectroscopy

5. The Neurobiology of Dopamine Signaling

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