Pliability in the m<sup>6</sup>A-Binding Region Extends Druggability of YTH Domains-Reference-Cited by-同舟云学术

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Pliability in the m⁶A-Binding Region Extends Druggability of YTH Domains

Published:2024-02-28 Issue:5 Volume:64 Page:1682-1690
ISSN:1549-9596
Container-title:Journal of Chemical Information and Modeling
language:en
Short-container-title:J. Chem. Inf. Model.

Author:

Cazzanelli Giulia¹,Dalle Vedove Andrea¹,Spagnolli Giovanni¹,Terruzzi Luca²^ORCID,Colasurdo Enrica²,Boldrini Alberto²,Patsilinakos Alexandros²,Sturlese Mattia³^ORCID,Grottesi Alessandro⁴,Biasini Emiliano¹,Provenzani Alessandro¹^ORCID,Quattrone Alessandro¹,Lolli Graziano¹^ORCID

Affiliation:

1. Department of Cellular, Computational and Integrative Biology─CIBIO, University of Trento, via Sommarive 9, 38123 Povo, Trento, Italy

2. Sibylla Biotech S.p.A, Via Lillo del Duca 10, 20091 Bresso, Milan, Italy

3. Department of Pharmaceutical and Pharmacological Sciences, University of Padova, Via Marzolo 5, 35131 Padova, Italy

4. CINECA, Via dei Tizii, 6, 00185 Roma, Italy

Funder

Alzheimer's Association

Associazione Italiana per la Ricerca sul Cancro

HORIZON EUROPE Marie Sklodowska-Curie Actions

AIL Trentino

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jcim.4c00051

Reference31 articles.

1. An epitranscriptomic vulnerability in myeloid malignancies

2. Meddling with METTLs in Normal and Leukemia Stem Cells

3. The Biology of m6A RNA Methylation in Normal and Malignant Hematopoiesis

4. The N6-methyladenosine (m6A)-forming enzyme METTL3 controls myeloid differentiation of normal hematopoietic and leukemia cells

5. METTL14 Inhibits Hematopoietic Stem/Progenitor Differentiation and Promotes Leukemogenesis via mRNA m6A Modification

Cited by 1 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. The three YTHDF paralogs and VIRMA are the major tumor drivers among the m⁶A core genes in a pan-cancer analysis;2024-06-13

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