Discovery of Potent Selective HDAC6 Inhibitors with 5-Phenyl-1<i>H</i>-indole Fragment: Virtual Screening, Rational Design, and Biological Evaluation-Reference-Cited by-同舟云学术

Discovery of Potent Selective HDAC6 Inhibitors with 5-Phenyl-1H-indole Fragment: Virtual Screening, Rational Design, and Biological Evaluation

Published:2024-07-23 Issue:15 Volume:64 Page:6147-6161
ISSN:1549-9596
Container-title:Journal of Chemical Information and Modeling
language:en
Short-container-title:J. Chem. Inf. Model.

Author:

Li Xuedong¹,Wang Chengzhao²,Chai Xu¹,Liu Xingang¹,Qiao Kening¹,Fu Yan¹,Jin Yanzhao³,Jia Qingzhong¹,Zhu Feng¹⁴^ORCID,Zhang Yang¹

Affiliation:

1. School of Pharmacy, Hebei Medical University, Shijiazhuang 050017, PR China

2. College of Basic Medicine, Hebei Medical University, Shijiazhuang 050017, PR China

3. Shijiazhuang Xianyu Digital Biotechnology Co., Ltd, Shijiazhuang 050024, PR China

4. College of Pharmaceutical Sciences, National Key Laboratory of Advanced Drug Delivery and Release Systems, The Second Affiliated Hospital, Zhejiang University School of Medicine, Zhejiang University, Hangzhou 310058, PR China

Funder

Natural Science Foundation of Hebei Province

Hebei Provincial Postdoctoral Science Foundation

Hebei Medical University

Department of Education of Hebei Province

Hebei Provincial Department of Science and Technology

Central Guidance on Local Science and Technology Development Fund of Hebei Province

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jcim.4c01052

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