In Silico Observation of the Conformational Opening of the Glutathione-Binding Site of Microsomal Prostaglandin E2 Synthase-1-Reference-Cited by-同舟云学术

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In Silico Observation of the Conformational Opening of the Glutathione-Binding Site of Microsomal Prostaglandin E2 Synthase-1

Published:2019-08-20 Issue:9 Volume:59 Page:3839-3845
ISSN:1549-9596
Container-title:Journal of Chemical Information and Modeling
language:en
Short-container-title:J. Chem. Inf. Model.

Author:

Zhou Shuo,Zhou Ziyuan,Ding Kai,Yuan Yaxia,Zheng Fang,Zhan Chang-Guo^ORCID

Funder

Division of Chemistry

Molecular Modeling and Biopharmaceutical Center, University of Kentucky College of Pharmacy

Publisher

American Chemical Society (ACS)

Subject

Library and Information Sciences,Computer Science Applications,General Chemical Engineering,General Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jcim.9b00289

Reference54 articles.

1. Success of prostaglandin E2 in structure-function is a challenge for structure-based therapeutics

2. Microsomal prostaglandin E synthase-1 and 5-lipoxygenase: potential drug targets in cancer

3. Microsomal prostaglandin E synthase 1 determines tumor growth in vivo of prostate and lung cancer cells

4. Perspective of microsomal prostaglandin E2 synthase-1 as drug target in inflammation-related disorders

5. Prostaglandin E Synthase, a Terminal Enzyme for Prostaglandin E2 Biosynthesis

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