Inhibitory Activity of Flavonoid Scaffolds on SARS-CoV-2 3CLpro: Insights from the Computational and Experimental Investigations

Author:

Khamto Nopawit12,Utama Kraikrit13,Boontawee Panida12,Janthong Atchara4,Tatieng Suriya5,Arthan Supakorn6,Choommongkol Vachira7,Sangthong Padchanee18,Yenjai Chavi9ORCID,Suree Nuttee18,Meepowpan Puttinan1810ORCID

Affiliation:

1. Department of Chemistry, Faculty of Science, Chiang Mai University, 239 Huay Kaew Road, Chiang Mai 50200, Thailand

2. Multidisciplinary and Interdisciplinary School, Chiang Mai University, 239 Huay Kaew Road, Chiang Mai 50200, Thailand

3. Office of Research Administration, Chiang Mai University, 239 Huay Kaew Road, Chiang Mai 50200, Thailand

4. Program in Biotechnology, Multidisciplinary and Interdisciplinary School, Chiang Mai University, 239 Huay Kaew Road, Chiang Mai 50200, Thailand

5. Department of Plant and Soil Sciences, Faculty of Agriculture, Chiang Mai University, 239 Huay Kaew Road, Chiang Mai 50200, Thailand

6. Program of Chemistry, Faculty of Science and Technology, Sakon Nakhon Rajabhat University, Sakon Nakhon47000, Thailand

7. Department of Chemistry, Faculty of Science, Maejo University, 63 Nong Han, Chiang Mai 50290, Thailand

8. Center of Excellence in Materials Science and Technology, Chiang Mai University, 239 Huay Kaew Road, Chiang Mai 50200, Thailand

9. Natural Products Research Unit, Department of Chemistry and Center of Excellence for Innovation in Chemistry, Faculty of Science, Khon Kaen University, 123, Khon Kaen 40002, Thailand

10. Center of Excellence for Innovation in Chemistry (PERCH-CIC), Faculty of Science, Chiang Mai University, 239 Huay Kaew Road, Chiang Mai 50200, Thailand

Funder

Chiang Mai University

Graduate School, Chiang Mai University

Department of Chemistry, Faculty of Science, Chiang Mai University

Faculty of Science, Chiang Mai University

National Research Council of Thailand

Materials Science Research Center, Faculty of Science, Chiang Mai University

Publisher

American Chemical Society (ACS)

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