Computational Peptide Design Cotargeting Glucagon and Glucagon-like Peptide-1 Receptors
Author:
Affiliation:
1. Department of Physics, Bernal Institute, University of Limerick, Limerick V94T9PX, Ireland
2. Merck, Kenilworth, New Jersey 07033, United States
3. Merck, West Point, Pennsylvania 19486, United States
Funder
Science Foundation Ireland
Publisher
American Chemical Society (ACS)
Subject
Library and Information Sciences,Computer Science Applications,General Chemical Engineering,General Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.jcim.3c00752
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1. Structure-Function of the G Protein–Coupled Receptor Superfamily
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3. G Protein-Coupled Receptors as Targets for Approved Drugs: How Many Targets and How Many Drugs?
4. MEDI0382, a GLP-1 and glucagon receptor dual agonist, in obese or overweight patients with type 2 diabetes: a randomised, controlled, double-blind, ascending dose and phase 2a study
5. GLP-1/glucagon receptor co-agonism for treatment of obesity
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