Hotspot Identification and Drug Design of Protein–Protein Interaction Modulators Using the Fragment Molecular Orbital Method-Reference-Cited by-同舟云学术

Hotspot Identification and Drug Design of Protein–Protein Interaction Modulators Using the Fragment Molecular Orbital Method

Published:2022-08-08 Issue:16 Volume:62 Page:3784-3799
ISSN:1549-9596
Container-title:Journal of Chemical Information and Modeling
language:en
Short-container-title:J. Chem. Inf. Model.

Author:

Monteleone Stefania¹,Fedorov Dmitri G.²^ORCID,Townsend-Nicholson Andrea³^ORCID,Southey Michelle¹,Bodkin Michael¹,Heifetz Alexander¹^ORCID

Affiliation:

1. Evotec UK Ltd., 114 Innovation Drive, Milton Park, Abingdon, Oxfordshire OX14 4RZ, United Kingdom

2. Research Center for Computational Design of Advanced Functional Materials (CD-FMat), National Institute of Advanced Industrial Science and Technology (AIST), 1-1-1 Umezono, Tsukuba, Ibaraki 305-8568, Japan

3. Institute of Structural & Molecular Biology, Research Department of Structural & Molecular Biology, Division of Biosciences, University College London, London WC1E 6BT, United Kingdom

Funder

H2020 Research Infrastructures

Publisher

American Chemical Society (ACS)

Subject

Library and Information Sciences,Computer Science Applications,General Chemical Engineering,General Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jcim.2c00457

Reference94 articles.

1. Fundamentals of protein interaction network mapping

2. Analyzing Protein–Protein Interaction Networks

3. Recent advances in the development of protein–protein interactions modulators: mechanisms and clinical trials