Impact of Mutations on NPAC Structural Dynamics: Mechanistic Insights from MD Simulations-Reference-Cited by-同舟云学术

Impact of Mutations on NPAC Structural Dynamics: Mechanistic Insights from MD Simulations

Published:2019-08-13 Issue:9 Volume:59 Page:3927-3937
ISSN:1549-9596
Container-title:Journal of Chemical Information and Modeling
language:en
Short-container-title:J. Chem. Inf. Model.

Author:

Montefiori Marco¹,Pilotto Simona²,Marabelli Chiara²,Moroni Elisabetta¹,Ferraro Mariarosaria¹^ORCID,Serapian Stefano A.³,Mattevi Andrea²^ORCID,Colombo Giorgio¹³^ORCID

Affiliation:

1. ICRM-CNR, Via Mario Bianco 9, 20131 Milano, Italy

2. Department of Biology and Biotechnology, University of Pavia, Via Ferrata 9, 27100 Pavia, Italy

3. University of Pavia, Department of Chemistry, V.le Taramelli 12, 27100 Pavia, Italy

Funder

Ministero dell?Istruzione, dell?Universit? e della Ricerca

Publisher

American Chemical Society (ACS)

Subject

Library and Information Sciences,Computer Science Applications,General Chemical Engineering,General Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jcim.9b00588

Reference34 articles.

1. Nuclear protein NP60 regulates p38 MAPK activity

2. LSD2/KDM1B and Its Cofactor NPAC/GLYR1 Endow a Structural and Molecular Model for Regulation of H3K4 Demethylation

3. Identification of NPAC as a novel biomarker and regulator for hepatocellular carcinoma

4. Human LSD2/KDM1b/AOF1 Regulates Gene Transcription by Modulating Intragenic H3K4me2 Methylation

5. A Tail-Based Mechanism Drives Nucleosome Demethylation by the LSD2/NPAC Multimeric Complex

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