Chromatography- and Lyophilization-Free Synthesis of a Peptide-Linker Conjugate-Reference-Cited by-同舟云学术

Chromatography- and Lyophilization-Free Synthesis of a Peptide-Linker Conjugate

Published:2014-01-06 Issue:1 Volume:18 Page:142-151
ISSN:1083-6160
Container-title:Organic Process Research & Development
language:en
Short-container-title:Org. Process Res. Dev.

Author:

Magano Javier¹,Bock Brandon²,Brennan John¹,Farrand Douglas²,Lovdahl Michael²,Maloney Mark T.¹,Nadkarni Durgesh³,Oliver Wendy K.²,Pozzo Mark J.⁴,Teixeira John J.¹,Wang Jian²,Rizzo John⁵,Tumelty David⁵

Affiliation:

1. Chemical Research & Development, Pfizer Worldwide Research & Development, Eastern Point Road, Groton, Connecticut 06340, United States

2. Analytical Research & Development, Pfizer Worldwide Research & Development, Eastern Point Road, Groton, Connecticut 06340, United States

3. Biotherapeutics Pharmaceutical Sciences, Pfizer Worldwide Research & Development, 401 North Middletown Road, Pearl River, New York 10965, United States

4. Biotherapeutics Pharmaceutical Sciences, Pfizer Worldwide Research & Development, 700 Chesterfield Parkway West, Chesterfield, Missouri 63017, United States

5. CovX Research, 9381 Judicial Drive, San Diego, California 92121, United States

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/op4002998

Reference37 articles.

1. Bioconjugation in pharmaceutical chemistry

2. Maleimide spacers as versatile linkers in the synthesis of bioconjugates of anthracyclines

3. Attachment of rhodosaminylanthracyclinone-type anthracyclines to the hinge-region of monoclonal antibodies

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