Strong Reduction of the Chain Rigidity of Hyaluronan by Selective Binding of Ca2+ Ions

Author:

Giubertoni Giulia1ORCID,Pérez de Alba Ortíz Alberto2ORCID,Bano Fouzia3ORCID,Zhang Xing4,Linhardt Robert J.4ORCID,Green Dixy E.5,DeAngelis Paul L.5,Koenderink Gijsje H.6ORCID,Richter Ralf P.3ORCID,Ensing Bernd2ORCID,Bakker Huib J.1ORCID

Affiliation:

1. AMOLF, Science Park 104, 1098 XG Amsterdam, The Netherlands

2. Van’t Hoff Institute for Molecular Sciences, University of Amsterdam, P.O. Box 94157, 1090 GD Amsterdam, The Netherlands

3. School of Biomedical Sciences, Faculty of Biological Sciences, School of Physics and Astronomy, Faculty of Engineering and Physical Sciences, Astbury Centre of Structural Molecular Biology, and Bragg Centre for Materials Research, University of Leeds, LS2 9JT Leeds, U.K.

4. Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, 110 8th Street, Troy, 12180 New York, United States

5. Department of Biochemistry and Molecular Biology, University of Oklahoma Health Sciences Center, 940 Stanton L. Young Blvd., Oklahoma, 73104 Oklahoma, United States

6. Department of Bionanoscience, Kavli Institute of Nanoscience Delft, Delft University of Technology, Van der Maasweg 9, 2629 HZ Delft, The Netherlands

Funder

Consejo Nacional de Ciencia y Tecnolog?a

Biotechnology and Biological Sciences Research Council

Nederlandse Organisatie voor Wetenschappelijk Onderzoek

Publisher

American Chemical Society (ACS)

Subject

Materials Chemistry,Inorganic Chemistry,Polymers and Plastics,Organic Chemistry

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